REWIRE envisions a holistic framework for continuous security assessment of open-source and open-specification hardware and software for IoT devices and the development of cybersecurity certification in accordance with the requirements and guidelines of recent EU regulation Cyber security Act3. The proposed scalable and multifunctional cybersecurity platform will ensure the security throughout the life of the IoT devices with continuous security auditing, trust computing and theorem proofs for defining an hw-based microarchitecture for enhanced protection targeting to open-hardware/software vulnerabilities. A certification procedure of the audited software and hardware components will propose new software security metrics and establish a layer of trust between stakeholders, utilizing Blockchain and smart contracts. REWIRE will expand traditional cyber insurance models to account for both open-source hardware and software assets, by ingesting security auditing results for estimating premium costs. REWIRE will exploit a Knowledge Plane of metadata generated from application behavioral patterns and operations to determine appropriate security policies and properties to enforce on open-source hw/sw to block potentially harmful instructions. REWIRE has invested in three carefully selected pilots (Automotive, Smart Cities, Smart Satellites), which can address the ambitious objectives of the project. - customizable TEE based on RISC-V - micro benchmarking for quick and automated assessment of h/w vulnerability Based on the above description, REWIRE aims to safeguard the entire workflow of secure processing; from the Deployment and Operation of SW-based SoSes to their patch management when new exploits have been identified during run-time, by providing new trust management mechanisms towards the auditability and certification of SW/HW open-source specifications.

Spinal cord injury is a severe and devastating neurological disorder that leaves patients with permanent paralysis of the body. No treatment is available today to regenerate interrupted nerve fibers and repair the damaged spinal cord. The incidence of spinal cord injury is about newly injured 10’000 people per year in the EU, and due to an almost normal life expectancy more than 200’000 patients are living with a spinal cord injury in the EU. The impact on the individual quality of life is high, and social costs are enormous. Recent preclinical research in animal models succeeded to greatly enhance axonal sprouting, fiber regeneration and neuroplasticity following injuries of brain and spinal cord. These results warrant translation now to patients suffering from acute spinal cord injury. A previous phase I clinical study using intrathecal application of a nerve fiber growth promoting antibody against the growth inhibitory protein Nogo-A has shown in patients with complete spinal cord injury that this treatment is safe and well tolerated. The present study will enroll patients with various degrees of complete to incomplete acute spinal cord injury for a double-blind, placebo-controlled trial to test the efficacy of this antibody therapy to improve motor outcome and quality of life of tetraplegic patients. The enrollment of patients with different degrees of spinal cord injury is considered essential to reveal drug activity and eventual proof of concept in a broad patient population. Advancements in clinical trial design, improved prediction algorithms of clinical outcomes and development of surrogate markers (in cerebro-spinal fluid/serum and by neuroimaging) will allow for scrutinizing the effectiveness of this novel treatment in an unprecedented way. A positive outcome of this trial will represent a breakthrough for the future therapy of spinal cord injuries and beyond (traumatic brain injury, stroke, multiple sclerosis).

<< Objectives >>INADE has following objectives:-blend German know-how in formal adult education, dual system, with Italian know-how in non formal/ informal adult learning opportunities, -refine high quality learning opportunities for adults with a focus change on environment/waste water and digital sector-provide tools and recommendations that can be used for and with our target group-develop an overarching framework transferable across Europeaiming to bring adult education closer to the environment<< Implementation >>We will exchange best practice and know-how in order to bring adult education closer to the environment, produce some results which help increase learning opportunities for adults, in the context of digital transformation. We will use digital platforms to transit EU values of education, participation and expression of opinion on digital, we will organise seminars and online events dedicated to adult education and environmental protection<< Results >>The project will produce several concrete outputs:-an Analysis of actual limitations and bottlenecks of learning/ training opportunities for adults, how the problem can be tackled through transnational partnership-The MEF, a modern education framework for high quality learning opportunities for adults adapted to adult needs, in the context of present EU challenges, incorporating digital utilities.