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Supporting Information: Aspergillus niger ochratoxinase is a highly specific, metal-dependent amidohydrolase suitable for OTA biodetoxification in food and feed

Authors: Sánchez-Arroyo, Ana; Plaza-Vinuesa, Laura; De Las Rivas, Blanca; Mancheño, Jose M.; Muñoz, Rosario;

Supporting Information: Aspergillus niger ochratoxinase is a highly specific, metal-dependent amidohydrolase suitable for OTA biodetoxification in food and feed

Abstract

Scheme of the hydrolysis of the amide bond of OTA, SDS-PAGE analysis of recombinant AnOTA from A. niger CBS 513.88, structural comparison of the AnOTA subunit with those from its close structural homologues, structures of the substrates used in our study classified into five families and also those of OTA and 4MF, docking of OTA into the cryoEM 3D structure of the AnOTA homologue enzyme ADH3 from S. acidaminiphila (SaOTA) and comparison with the experimentally determined structure of the mycotoxin, and SDS-PAGE analysis of plant-based beverages containing OTA (5 μM) incubated with AnOTA at 37 °C for 18 h.

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average