Universal methyl donor, Terminal tails, Healthy tissue samples, Adenosyl methionine, Human cells independently, Cancer cell lines, Primary tumour samples, Results suggest, Histone methylation, Enzyme previously characterised, Multiple histone marks, Chromatin genome, Detectable impact, div >< p, Alternative methyl sink, Histone methyltransferases, Frequently posttranslationally modified, Healthy tissues, Methyl sink, Associations affected, Human cells, Eukaryotic histones, Adomet, Less clear, Different associations, Enzymatic processes, Seq data, Inversely correlated, Tumour suppressor