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handle: 10261/352335
Left panel, Western blot for NDUFV1 (N module) and NDUFA9 (Q module). ATP5B and Coomassie staining were used as loading controls. Right panel, schematic representation of CI. The N module contains an NADH oxidation site, while the Q module contains a ubiquinone reduction site. P module is involved in proton-pumping activity. The positions of NDUFV1 and NDUFA9 are indicated. IMM, inner mitochondrial membrane; IMS, intermembrane space.
Peer reviewed
Effector functions, Shift towards, Maximal respiration Vitro </, Modulatory role, Lipopolysaccharide challenge, Improved ability, Supernumerary subunit, Mutational hotspot, Atp production, Increasing evidence demonstrate, Lower levels, Div >< p, Leigh syndrome patients, Phagocytose gram, Critical role, Ndufs4 </, Macrophage effector functions, Inflammatory cytokine profile, Mitochondrial respiration alterations
Effector functions, Shift towards, Maximal respiration Vitro </, Modulatory role, Lipopolysaccharide challenge, Improved ability, Supernumerary subunit, Mutational hotspot, Atp production, Increasing evidence demonstrate, Lower levels, Div >< p, Leigh syndrome patients, Phagocytose gram, Critical role, Ndufs4 </, Macrophage effector functions, Inflammatory cytokine profile, Mitochondrial respiration alterations
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