Downloads provided by UsageCountsThe 3Dpol-3B complexes [Dataset]
Ferrer-Orta, Cristina; Ferrero, Diego; Verdaguer, Núria;
The 3Dpol-3B complexes [Dataset]
(A) Cartoon representation of the structure of the FMDV 3Dpol-3B3 complex from trigonal crystals, space group P3221. 3Dpol is shown in ribbons (yellow) and the VPg3 fragment, bound at the bottom of the palm subdomain, is shown as atom type stick (carbons in white). The corresponding 2Fo-Fc electron density map (1.0σ) is also shown around the 3B3 molecule as a light blue mesh. The proximity of a neighbouring 3Dpol molecule (Grey) in the crystal packing probably limits the 3B molecule from being arranged in an ordered way. (B) The Structure of the EV71-3B in complex with 3Dpol. 3Dpol is shown in orange ribbons and the bound VPg is depicted as atom-type sticks at the bottom of palm sub-domain [11] (PDB id 4IKA). (C) Detail of the interactions in the FMDV 3Dpol-3B3 complex.
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Almost symmetric way, Higher binding affinity, Another critical interaction, Replication machinery, Based pull, Two uridine molecules pol, Replication occurs, Replication complex, Play essential roles, Animal pathogen foot, Region ii, Also catalysed, 3b uridylylation, div >< p, Mouth disease virus, Fmdv 3b1, Replication requires, Different functions within, Viral rna, Highest affinity, Identical copies, Essential component, Structural biology approaches, Pol, 3b1 complex, Linked immunosorbent assays, Assays show, Functional binding, Basic residues, Picornavirus replication, Concentrate viral rna, Region ii presenting, Binding protein responsible, Elisa assays show, Protein primer, Host factors, Dependent rna polymerase, Small protein, 3b1 region ii, Also participate, Membranous compartments, Pprimer protein 3b
Almost symmetric way, Higher binding affinity, Another critical interaction, Replication machinery, Based pull, Two uridine molecules pol, Replication occurs, Replication complex, Play essential roles, Animal pathogen foot, Region ii, Also catalysed, 3b uridylylation, div >< p, Mouth disease virus, Fmdv 3b1, Replication requires, Different functions within, Viral rna, Highest affinity, Identical copies, Essential component, Structural biology approaches, Pol, 3b1 complex, Linked immunosorbent assays, Assays show, Functional binding, Basic residues, Picornavirus replication, Concentrate viral rna, Region ii presenting, Binding protein responsible, Elisa assays show, Protein primer, Host factors, Dependent rna polymerase, Small protein, 3b1 region ii, Also participate, Membranous compartments, Pprimer protein 3b
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