Supplemental Material Fine-tuning of the Hsc70-based human protein disaggregase machinery by the distinctive C-terminal extension of Apg2

Authors: Cabrera, Yovana; Bernardo-Seisdedos, Ganeko; Dublang, Leire; Albesa-Jové, David; Orozco, Natalia; Viguera, Ana Rosa; Millet, Óscar; +2 Authors

handle: 10261/331446

Supplemental Material Fine-tuning of the Hsc70-based human protein disaggregase machinery by the distinctive C-terminal extension of Apg2

- Summary
- Metrics

Abstract

8 pages. -- Table 1. SAXS data collection and processing. -- Figure S1: Binding of nucleotides does not promote significant conformational changes in Apg2 and Apg2C tertiary structure. -- Figure S2: Characterization of the interaction of Apg2ΔC with Hsc70 in the absence of nucleotides by SPR. -- Fig. S3: NMR chemical shift perturbation analysis. -- Fig- S4: Apg2IDR interacts with Hsc70 with 2-fold reduced affinity in the presence of nucleotides.

Peer reviewed

Country

Spain

Related Organizations

Spanish National Research Council
Spain

Impact byBIP!

	selected citations These citations are derived from selected sources. This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	0
	popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.	Average
	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Average
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Average

Usage byUsageCounts

visibility	views	51
download	downloads	30

51
views
30
downloads
Powered by

Found an issue? Give us feedback

visibility

download

0

Average

51

30