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Supplementary Figures Modeling microRNA-driven post-transcriptional regulation by using exon-intron split analysis (EISA) in pigs

Authors: Mármol-Sánchez, Emilio; Cirera, Susanna; Zingaretti, Laura M.; Jacobsen, Mette Juul; Ramayo-Caldas, Yuliaxis; Jørgensen, C. B.; Fredholm, Merete; +3 Authors

Supplementary Figures Modeling microRNA-driven post-transcriptional regulation by using exon-intron split analysis (EISA) in pigs

Abstract

8 pages. -- 5 figures. -- Figure S1: Diagram depicting the routine/pipeline implemented for studying miRNAdriven post-transcriptional regulatory signals applying the EISA approach and additional enrichment and covariation analyses. -- Figure S2: Diagram representing each one of the context-based filtering criteria used for excluding unreliable in silico-predicted miRNA-mRNA interactions. -- Figure S3: Scatterplots depicting the exonic (ΔEx) and intronic (ΔInt) fractions of expressed genes from gluteus medius skeletal muscle samples of fasting (AL-T0, N =11) and fed (AL-T2, N = 12) Duroc gilts. -- Figure S4: Enrichment analyses comparing all expressed mRNA genes and the set of mRNA genes with the (a) top 1% and (b) top 5% negative PTc scores and at least 2-fold ΔEx reduction as being putatively targeted by significantly upregulated miRNAs (FC > 1.5; q-value < 0.05) from gluteus medius skeletal muscle samples of fasting (AL-T0, N =11) and fed (AL-T2, N = 12) Duroc gilts. -- Figure S5: Quantification of selected genes and miRNAs expressed in the pig adipose tissue by qPCR.

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
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Average