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Cytokine production by TLR7lig-Pp3 and TLR7lig

Research datakeyboard_double_arrow_right Dataset 01 Jan 2021Embargo end date: 14 Jun 2021 Spain English Publisher:Digital.CSIC

Authors: Losada Méndez, Jorge; Palomares, Francisca; Gómez, Francisca; Ramírez-López, Pedro; Ramos-Soriano, Javier; Torres, María José; Mayorga, Cristobalina; +1 Authors

doi: 10.20350/digitalcsic/13903

handle: 10261/243314

Cytokine production by TLR7lig-Pp3 and TLR7lig

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Abstract

Production of cytokine into the culture supernatant from DCs. Our analysis in allergic patients compared to tolerant controls detected significant increases of IL-5 and IFN with all the conditions containing TLR7lig (TLR7lig, TLR7lig-Pp3 and TLR7lig plus Pp3 in separately way). we observed that TLR7lig-Pp3 induced significant lower IL-4 and IL-5 levels whilst higher IFNγ levels compared to the Pp3 only in allergic patients, indicating the specific immunomodulatory capacity of this compound.

Peer reviewed

Country

Spain

Related Organizations

Spanish National Research Council
Spain

Keywords

Cytokines type 2 and type 1 immnune response, Cell culture, Dendritic cells

1 Research products, page 1 of 1

Maturation and activation dendritic cells by the TLR7lig-Pp3 and TLR7lig
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