This folder contains isoTWAS and TWAS models for adult brain cortex using data from Gandal et al 2018, Science and Vialle et al 2022, Nature Neuroscience (June 2023). The folder contains two subfolders with .RDS files for isoTWAS and TWAS models and a third subfolder that contains .RDS files for in-sample LD matrices corresponding to each model. Models were trained using R package isotwas (github.com/bhattacharya-a-bt/isotwas). Please note that updated TWAS models are available at https://zenodo.org/records/10642062; isoTWAS models remain equivalent across these two releases.