The "Dati_connettivita_Triple_Network_Model.xlsx" database includes clinical and MRI connectivity data from a sample of 91 patients Chronic Migraine associated with Medication Overuse Headache and 35 controls. The reported data consist of: demographic data (i.e., Age and Sex assigned at birth), clinical data (i.e., overused medications, depression, anxiety, allodynia, chronification, disease duration, medication intake), and intra- and inter-network connectivity information on the Default Mode Network, Salience Network, and Central Executive Network.