
This Zenodo deposit contains a publicly available description of the Dataset: Title: "PD5D_MTG_snRNAseq_hybsel". Description: This dataset contains the raw data in FASTQ format for single-nucleus RNA sequencing (snRNAseq) enriched with Agilent SureSelect for reads from a list of targeted transcripts for human middle temporal gyrus (MTG) samples from Parkinson's patients and healthy controls. This data comes from the same 10X libraries as PD5D_MTG_snRNAseq, except with the additional enrichment step before sequencing. It's part of the PD5D cohort, where the same subjects were also profiled with other omics assays incl. genotyping, single-cell ATACseq, and spatial transcriptomics. This dataset is made available to researchers via the ASAP CRN Cloud: cloud.parkinsonsroadmap.org. Instructions for how to request access can be found in the User Manual. This research was funded by the Aligning Science Across Parkinson's Collaborative Research Network (ASAP CRN), through the Michael J. Fox Foundation for Parkinson's Research (MJFF). This Zenodo deposit was created by the ASAP CRN Cloud staff on behalf of the dataset authors. It provides a citable reference for a CRN Cloud Dataset Dataset Metadata was updated for the v1.1 update Version bump from 1.1 to 1.2 The updated Datasets fix inconsistencies in the ASAP assigned `ASAP_subject_id` and `ASAP_sample_id` for these previously released PMDBS Datasets. These erroneously included the string "PMBDS", now replaced with "PMDBS". This change does not affect the underlying data files, but does update the metadata to be consistent with the naming convention used for all other PMDBS Datasets and the corresponding CDEs.
