This article examines the morphological features of pollen grains from medicinal plants belonging to the Lamiaceae family, using the Samarkand region as a case study. The objective of this work is the palynological analysis of pollen grains from plant species of the Lamiaceae family and the determination of their systematic significance based on diagnostic characteristics. The research employed classical palynological and microscopic analysis methods. In the samples studied, the shape, size, number and type of apertures, exine structure, and surface ornamentation were identified and compared. This study is of significant importance for the scientific description of medicinal plants found in the Samarkand region, for clarifying their systematic position, and for the advancement of palynological research.