Digital technologies have become one of the most important drivers of economic transformation in the modern global economy. Their rapid diffusion has significantly influenced regional development by improving productivity, stimulating innovation, and reshaping the structure of local economies. This article analyzes the impact of digital technologies on regional economic growth, focusing on how digital infrastructure, technological innovation, and human capital contribute to economic modernization. The study also examines the challenges associated with digital transformation, including the digital divide, regional inequality, and structural changes in labor markets. Based on the analysis of recent empirical studies and international experience, the research highlights that the successful integration of digital technologies into regional economies requires supportive institutional frameworks, investment in digital infrastructure, and the development of digital skills. The findings indicate that while digital technologies offer significant opportunities for sustainable and inclusive growth, their benefits depend largely on the ability of regions to build strong innovation ecosystems and effective governance mechanisms.