Dermal exposure assessment dataset focuses on NM deposition and release under simulated use conditions. Laboratory tests were conducted to quantify dermal exposure (release rates) using the Crockmeter (EN ISO 105 X12:2016 – Part X12), simulating dermal contact abrasion and measuring Ti release (ng/cm²) for both unwashed and washed samples. The dataset quantifies Ti release and retention after durability testing. The missing values are not actual data gaps but result from the dataset structure, where the last columns separately record cotton concentration from released particles and remaining Ti in the textile considering different sample dimension and number of fabric pieces processed. The apparent similarity in missing data arises because identical experiments are represented, but with different output variables recorded independently.