The MIBiG (Minimum Information about a Biosynthetic Gene Cluster) Repository stores Biosynthetic Gene Clusters (BGC) that are manually curated through community efforts. It is a central reference database for BGCs of known function, and provides the basis for comparative analyses for a number of tools. It has enabled many computational analyses of BGC function and novelty central to both small and large-scale studies of microbes and microbial communities.
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The Jackson Laboratory Clinical Knowledgebase (CKB) is a semi-automated/manually curated database of gene/variant annotations, therapy knowledge, diagnostic/prognostic information, and clinical trials related to oncology. CKB not only contains current information on the protein effect of somatic gene variants, but also connects the variant to targeted therapies through an efficacy evidence annotation. In addition, CKB captures clinical trial patient eligibility criteria that include genomic alterations (genotype-specific). The public access version of CKB encompasses 82 commonly known driver genes. Users can search CKB via gene, gene variants, drug, drug class, indication, and clinical trials. The web-based version of CKB is designed to interrogate the knowledgebase for specific data attributes while also enabling a robust browse like feature when the desired content is unknown.
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GlyConnect is a knowledgebase of glycoproteins spanning protein, glycosite and glycan information. It is a platform designed to investigate the relationships between glycans, the proteins that carry them and the proteins that bind them via the UniLectin sister project. The underlying database stores curated data on glycosylation extracted from literature and preserving the contextual information relative to species, original cell line, tissue and disease. GlyConnect is the central resource of the Glyco@Expasy collection hosted at SIB - Swiss Institute of Bioinformatics.
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re3data: r3d100012420
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This site provides access to the theses and dissertation output of the institution from 2003. The interface is in English.
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Mimotope database, active site-mimicking peptides selected from phage-display libraries. It is a database which stores information on peptides that have been selected from random peptide libraries based on their ability to bind small compounds, nucleic acids, proteins, cells, tissues, organs, and even entire organisms through phage display technology. Besides the peptide sequences, other information such as the corresponding target, template, library, and structures are also stored. All entries are manually extracted from published peer review articles and other public data sources such as Uniprot, GenBank and PDBSum.
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re3data: r3d100012975
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The MIBiG (Minimum Information about a Biosynthetic Gene Cluster) Repository stores Biosynthetic Gene Clusters (BGC) that are manually curated through community efforts. It is a central reference database for BGCs of known function, and provides the basis for comparative analyses for a number of tools. It has enabled many computational analyses of BGC function and novelty central to both small and large-scale studies of microbes and microbial communities.
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The Jackson Laboratory Clinical Knowledgebase (CKB) is a semi-automated/manually curated database of gene/variant annotations, therapy knowledge, diagnostic/prognostic information, and clinical trials related to oncology. CKB not only contains current information on the protein effect of somatic gene variants, but also connects the variant to targeted therapies through an efficacy evidence annotation. In addition, CKB captures clinical trial patient eligibility criteria that include genomic alterations (genotype-specific). The public access version of CKB encompasses 82 commonly known driver genes. Users can search CKB via gene, gene variants, drug, drug class, indication, and clinical trials. The web-based version of CKB is designed to interrogate the knowledgebase for specific data attributes while also enabling a robust browse like feature when the desired content is unknown.
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GlyConnect is a knowledgebase of glycoproteins spanning protein, glycosite and glycan information. It is a platform designed to investigate the relationships between glycans, the proteins that carry them and the proteins that bind them via the UniLectin sister project. The underlying database stores curated data on glycosylation extracted from literature and preserving the contextual information relative to species, original cell line, tissue and disease. GlyConnect is the central resource of the Glyco@Expasy collection hosted at SIB - Swiss Institute of Bioinformatics.
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This site provides access to the theses and dissertation output of the institution from 2003. The interface is in English.
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Mimotope database, active site-mimicking peptides selected from phage-display libraries. It is a database which stores information on peptides that have been selected from random peptide libraries based on their ability to bind small compounds, nucleic acids, proteins, cells, tissues, organs, and even entire organisms through phage display technology. Besides the peptide sequences, other information such as the corresponding target, template, library, and structures are also stored. All entries are manually extracted from published peer review articles and other public data sources such as Uniprot, GenBank and PDBSum.
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