software . 2010

Drosophila Phototransduction Simulator

Nikolic, K; Loizu, J;
Open Access
  • Published: 31 Dec 2010
  • Country: United Kingdom
This code contains detailed modelling of the single photon response, the quantum bump, of fly photoreceptors. All known components participating in the primary phototransduction process are taken into account, and estimates are given for the both the physical and the chemical parameters. The same model can be used for multiphoton response, i.e. in the case of higher light intensity stimuli. The model successfully reproduces the experimental results for the statistical features of quantum bumps (average shape, peak current average value and variance, the latency distribution, etc), arrestin mutant behaviour, low extracellular Ca cases, etc. The TRP channel activi...
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