software . 2018

DeepCRISPR: optimized CRISPR guide RNA design by deep learning

Chuai, Guohui; Liu, Qi;
Open Source
  • Published: 01 Jan 2018
  • Publisher: Zenodo
Abstract
<p>DeepCRISPR is a deep learning based prediction model for sgRNA on-target knockout efficacy and genome-wide off-target cleavage profile prediction.</p> <p>This model is based on a carefully designed hybrid deep neural network for model training and prediction.</p> <p>Current version focuses on conventional NGG-based sgRNA design for SpCas9 in human species, for it is widely used in related experiments.</p>
Subjects
free text keywords: deep learning, CRISPR
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Zenodo
Software . 2018
Provider: Zenodo
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software . 2018

DeepCRISPR: optimized CRISPR guide RNA design by deep learning

Chuai, Guohui; Liu, Qi;