software . 2017

Pmharrison/Flps: Flps: Fast Discovery Of Compositional Biases For The Protein Universe

pmharrison;
Open Source
  • Published: 13 Sep 2017
  • Publisher: Zenodo
Abstract
Proteins often contain regions that are compositionally biased (CB), i.e., they are made from a small subset of amino-acid residue types. These CB regions can be functionally important, e.g., the prion-forming and prion-like regions that are rich in asparagine and glutamine residues. Here I report a new program fLPS that can rapidly annotate CB regions. It discovers both single-residue and multiple-residue biases. It works through a process of probability minimization. First, contigs are constructed for each amino-acid type out of sequence windows with a low degree of bias; second, these contigs are searched exhaustively for low-probability subsequences (LPSs); ...
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Open Access
Zenodo
Software . 2017
Provider: Datacite
Open Access
Zenodo
Software . 2017
Provider: Datacite
Open Source
Zenodo
Software . 2017
Provider: Zenodo
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