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The origins of SARS-CoV-2: A critical review

Authors: Edward C. Holmes; Stephen A. Goldstein; Angela L. Rasmussen; David L. Robertson; Alexander Crits-Christoph; Joel O. Wertheim; Simon J. Anthony; +14 Authors

The origins of SARS-CoV-2: A critical review

Abstract

The Origins of SARS-CoV-2: A Critical Review Holmes et al. Since the first reports of a novel SARS-like coronavirus in December 2019 in Wuhan, China, there has been intense interest in understanding how SARS-CoV-2 emerged in the human population. Recent debate has coalesced around two competing ideas: a “laboratory escape” scenario and zoonotic emergence. Here, we critically review the current scientific evidence that may help clarify the origin of SARS-CoV-2.

Keywords

Biomedical and clinical sciences, origins, Coronaviruses, Bioinformatics and Computational Biology, bats, 610, bat, Review, Medical and Health Sciences, Zoonoses, Chiroptera, 616, evolution, Animals, Humans, Animalia, Chordata, Lung, 11 Medical and Health Sciences, Biomedical and Clinical Sciences, SARS-CoV-2, COVID-19, Pneumonia, Biodiversity, Biological Sciences, 06 Biological Sciences, zoonosis, Biological Evolution, Coronavirus, Biological sciences, sars-cov-2, Emerging Infectious Diseases, Infectious Diseases, Good Health and Well Being, covid-19, Mammalia, Pneumonia & Influenza, Laboratories, Developmental Biology

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    selected citations
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    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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    Top 0.1%
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
views
OpenAIRE UsageCountsViews provided by UsageCounts
downloads
OpenAIRE UsageCountsDownloads provided by UsageCounts
405
Top 0.1%
Top 1%
Top 0.01%
2K
473
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