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Dataset . 2021
License: CC BY
Data sources: Datacite
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ZENODO
Dataset . 2021
License: CC BY
Data sources: Datacite
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ZENODO
Dataset . 2021
License: CC BY
Data sources: ZENODO
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A cerebellar internal model calibrates a feedback controller involved in sensorimotor control

Authors: Markov, Daniil A.; Petrucco, Luigi; Kist, Andreas M.; Portugues, Ruben;

A cerebellar internal model calibrates a feedback controller involved in sensorimotor control

Abstract

This upload contains datasets from the manuscript by Markov et al., 2021 "A cerebellar internal model calibrates a feedback controller involved in sensorimotor control" (preprint here; the code used to acquire and process these data can be found here). The datasets are organized in the following zip folders: behavioral_data.zip contains data from acute reaction and long-term adaptation experiments for wild-type control, treatment control, and Purkinje-cell-ablated zebrafish larvae feedback_control_model.zip contains parameters of the model after fitting it to the data acquired during the acute reaction experiment. PC_ablation_quantification.zip contains confocal images of the cerebella of zebrafish larvae before and after pharmaco-genetic ablation of Purkinje cells. reference_brain_stacks.zip contains z-stacks used for anatomical registration of the functional imaging data whole_brain_imaging_inetgrators.zip contains whole-brain light-sheet data acquired while zebrafish larvae were performing optomotor response to forward moving grating. This dataset was used to identify sensory integrators in the larval zebrafish brain PC_imaging_long_term_adaptation.zip contains light-sheet recordings of Purkinje cell activity acquired during long-term adaptation to lagged visual feedback. This dataset was used to identify signatures of internal models in the Purkinje cell activity. whole_brain_imaging_long_term_adaptation.zip contains whole-brain light-sheet recordings during long-term adaptation to lagged visual feedback. This dataset was used to study correlates of the long-term adaptation in the entire brain (such as change in sensory integration time constants). For any question about the data, please write at ruben.portugues@tum.de or daniil.markov@charite.de.

Keywords

motor learning, internal models, motor control, cerebellum, larval zebrafish, Purkinje cells

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popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
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influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
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