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The Pan-SL-CoV/GD sequences may be from contamination.

Authors: Daoyu Zhang;

The Pan-SL-CoV/GD sequences may be from contamination.

Abstract

ABSTRACT Recently, There were much hype about an alleged SARS-like coronavirus being found in samples of Malayan pangolins (Manis Javanica) possessing nearly identical RBD to the SARS-CoV-2 coronavirus. Prominent journals cite the alleged discovery to claim that pangolins may be one of a possible intermediate host for the zoonotic transmission of SARS-CoV-2 to humans. Here, we report that all databases used to support such a claim, upon which metagenomic analysis was possible, contained unexpected reads and was in serious risk of contamination. Here we also report that the presence of unexpected reads are directly related to the presence of coronavirus reads. Finally, we deduced the actual causative agent of the death of the pangolins sampled in GuangDong 2019 where the claim of coronavirus detections was made.

{"references": ["https://doi.org/10.1371/journal.ppat.1008421", "https://doi.org/10.1038/s41586-020-2313-x", "https://doi.org/10.1038/s41586-020-2169-0", "https://doi.org/10.1101/2020.01.30.917195", "https://doi.org/10.1016/j.actatropica.2017.12.003", "Hemorrhagic Fever-Causing Arenaviruses: Lethal Pathogens and Potent Immune Suppressors Morgan E. Brisse1,2 and Hinh Ly2,*", "Evolutionary origins of the SARS\u2010CoV\u20102sarbecovirus lineage responsible for the COVID-19 pandemicMaciej F Boni1*\uf023, Philippe Lemey2*\uf023, Xiaowei Jiang3, Tommy Tsan-Yuk Lam4, Blair Perry5, Todd Castoe5, Andrew Rambaut6\uf023 and David L Robertson7\uf023", "https://doi.org/10.1093/nsr/nwaa036"]}

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Keywords

Pan-SL-CoV, MP789, SRA, Sequence Reade Archive

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selected citations
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This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
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