ROS-Specific Huntingtin Interactions: Chromatin Retention of Huntingtin in PARP KO Cells

Dataset . 2019

License: CC BY

Data sources: Datacite

Dataset . 2019

License: CC BY

Data sources: Datacite

Research datakeyboard_double_arrow_right Dataset 20 Jun 2019 English Publisher:Zenodo

Authors: Maiuri, Tamara; Truant, Ray;

Abstract

Huntingtin chromatin retention in response to oxidative stress in wild type, PARP1 knockout, PARP2 knockout, and PARP1/PARP2 knockout RPE1 cells.

This work is funded by the HDSA Berman/Topper HD Career Development Fellowship.

Related Organizations

Keywords

reactive oxygen species, poly ADP ribose, intrabody, huntingtin, oxidative stress, Huntington's disease, ROS, chromatin retention assay, PARP

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