
This paper presents a translational concept for modulating biological age through the interaction of gut microbiome regulation and neurophysiological modulation mechanisms. The proposed framework explores the role of Saccharomyces spp. in supporting intestinal barrier function and immune homeostasis, alongside a neuroacoustic model of systemic regulation via central nervous system pathways. The concept is positioned as a space-health–relevant supportive system, with potential applicability both in extreme environments and terrestrial longevity-oriented technologies.
Key highlights: Molecularly Structured Protein Matrix (MSPM): Focused on microbiome–immune axis stability. Neuroacoustic Stimulation Protocol (NASP): Targeting autonomic nervous system balance. Context: This work is aligned with ongoing space-health research activities. The submitted proposal has been accepted for evaluation by The Translational Research Institute for Space Health (TRISH, Houston) under Reference ID: CAT3-0000000593.
Key highlights: Molecularly Structured Protein Matrix (MSPM): Focused on microbiome–immune axis stability. Neuroacoustic Stimulation Protocol (NASP): Targeting autonomic nervous system balance. Context: This work is aligned with ongoing space-health research activities. The submitted proposal has been accepted for evaluation by The Translational Research Institute for Space Health (TRISH, Houston) under Reference ID: CAT3-0000000593.
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