ABSTRACT: ECMO is a life sustaining therapy that provides both cardiac and respiratory support to patient with severe organ failure this highly specialized treatment uses a machine to take over the work of the lungs and heart, oxygenating the blood and pumping it throughout the body. ECMO issued in critically ill patients with condition such as acute respiratory distress syndrome (ARDS), cardiac arrest, and post craniotomy shock among others, by providing a temporary bridge to recovery ECMO has revolutionized the treatment of these complex patient and improved outcomes in many cases. One group pre-test post-test research design was adopted for the study, 60 BSc. Nursing students were selected as sample by non probability convenience sampling technique. The present study assess the effectiveness of video assisted teaching programmed. The study findings ,that there was a significant improvement in the level of knowledge after providing video assisted teaching program.