This document presents refined estimates of annual market opportunities in the European Union (EU) for 79 Use Case Solutions identified as significant and promising by the UNLOCK-CEI project. It builds on a detailed structural analysis methodology (presented in “White Paper 2.1: Technology Implementation Model and Architectural Patterns for CEI Use Cases”1, including a common technology implementation model and estimated costing scheme, applied to detailed analysis of market factors (including statistics on enterprises, employment and value added) for the five sectors considered by this project: agriculture, energy, healthcare, manufacturing and transport.