Dataset of electrocardiogram and electroencephalogram signals (.edf) acquired in epileptic patients (N=15). All the patients were long-term monitored with a Video-EEG, with electrodes arranged on the basis of the international 10-20 system, and with ECG. ECG was measured simultaneously with a sampling rate of 512 Hz. Each data include a descriptor file (.txt) containing all the information related to the acquisition: data, registration start (time), registration end (time), seizure/s start, seizure/s end and the electrodes involved at the seizure onset.