This deliverable presents the work carried out within Work Package 6 "Risk Management and Governance" and refers to Task 6.1 of the project, which aims to define effective risk management approaches for Multi-Component Nanomaterials (MCNMs) and High Aspect Ratio Nanoparticles (HARNs), considering their unique toxicological properties and various exposure scenarios in nanotechnology.Using the STOP principle, priority is given to strategic, technical, organizational, and personal protection measures. An interactive Risk Management Tool (RMT) has been developed to support regulators, industries, and other stakeholders on the selection of the best available approaches to reduce risk at source and mitigate the exposure at all stages of MCNMs and HARNs life cycle.Existing guidelines will be adapted, and data from various sources will be analysed. Hazard avoidance or reduction will be explored, followed by recommendations for product, process, and workplace control. Engineering controls and good work practices will be evaluated, along with individual protective equipment to mitigate risks.Additionally, the document also includes a user manual generated to explain the operation of the RMT with the aim of guiding the user.