Abstract The main part of the human body consists of water, and water plays the role of a favorable environment for all biochemical processes in the body. The beneficial or harmful effects of chemical substances entering the body are determined by their interaction with water. The use of harmful substances for the health of the body should be low enough. , the goal is to detect chemical substances that can be useful to the body. Considering that the main solvent in the human body is water, we can say that chemical substances that structure water should be detected. The main problem facing pharmacologists is to identify chemical substances that have a positive or negative effect on the structure of water in a short time. consists of. The physical quantity that accurately determines the effect of substances on the structure of water is structural temperature. Therefore, the concept of structural temperature and the development of its theory are of great importance for pharmacology. In the presented work, the main properties of water, its structure and the importance of structural temperature were discussed in detail. Finally, it should be noted that the determination of structural temperature is the most perfect method for the preparation of pharmacological substances in a short period of time.