These datasets are related to the Data Article entitled: “A benchmark dataset for the retail multiskilled personnel planning under uncertain demand”, submitted to the Data Science Journal. This data article describes datasets from a home improvement retailer located in Santiago, Chile. The datasets were developed to solve a multiskilled personnel assignment problem (MPAP) under uncertain demand. Notably, these datasets were used in the published article "Multiskilled personnel assignment problem under uncertain demand: A benchmarking analysis" authored by Henao et al. (2022). Moreover, the datasets were also used in the published articles authored by Henao et al. (2016) and Henao et al. (2019) to solve MPAPs. The datasets include real and simulated data. Regarding the real dataset, it includes information about the store size, number of employees, employment-contract characteristics, mean value of weekly hours demand in each department, and cost parameters. Regarding the simulated datasets, they include information about the random parameter of weekly hours demand in each store department. The simulated data are presented in 18 text files classified by: (i) Sample type (in-sample or out-of-sample). (ii) Truncation-type method (zero-truncated or percentile-truncated). (iii) Coefficient of variation (5, 10, 20, 30, 40, 50%).