descriptionPublicationkeyboard_double_arrow_right Article , Other literature type 19 Aug 2021Publisher:American Chemical Society (ACS)Journal:Organic Letters, volume 23, pages 9,337-9,342 (issn: 1523-7060, eissn: 1523-7052,

Authors: Michał Ociepa; Kyle W. Knouse; David He; Julien C. Vantourout; Dillon T. Flood; Natalia M. Padial; Jason S. Chen; +7 Authors

doi: 10.26434/chemrxiv-2021-4ksng , 10.1021/acs.orglett.1c02736 , 10.33774/chemrxiv-2021-4ksng

pmid: 34499517

pmc: PMC8733960

Mild and Chemoselective Phosphorylation of Alcohols Using a PSI-Reagent

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Abstract

An operationally simple, scalable, and chemoselective method for the direct phosphorylation of alcohols using a P(V)-approach based on the PSI-reagent platform is disclosed. The method features a broad substrate scope of utility in both simple and complex settings and provides access to valuable phosphorylated alcohols that would be otherwise difficult to access.

Related Organizations

Bristol Myers Squibb
University of Granada
Spain
Bristol-Myers Squibb (Portugal)
Portugal
Bristol-Myers Squibb (Switzerland)
Switzerland
Scripps Research Institute
United States

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Keywords

Molecular Structure, Alcohols, Indicators and Reagents, Phosphorylation, Catalysis

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