research data . Dataset . 2016

Defined three-dimensional culture conditions mediate efficient induction of definitive endoderm lineage from human umbilical cord Wharton’s jelly mesenchymal stem cells

Madhoun, Ashraf Al; Ali, Hamad; AlKandari, Sarah; Atizado, Valerie; Akhter, Nadeem; Al-Mulla, Fahd; Atari, Maher;
  • Published: 15 Dec 2016
  • Publisher: Figshare
Abstract
Abstract Background Wharton’s jelly-derived mesenchymal stem cells (WJ-MSCs) are gaining increasing interest as an alternative source of stem cells for regenerative medicine applications. Definitive endoderm (DE) specification is a prerequisite for the development of vital organs such as liver and pancreas. Hence, efficient induction of the DE lineage from stem cells is crucial for subsequent generation of clinically relevant cell types. Here we present a defined 3D differentiation protocol of WJ-MSCs into
Subjects
free text keywords: Biophysics, Biochemistry, Space Science, 29999 Physical Sciences not elsewhere classified, Cell Biology, Molecular Biology, Pharmacology, Biotechnology, 39999 Chemical Sciences not elsewhere classified, Developmental Biology, Cancer, Hematology, 110309 Infectious Diseases, Plant Biology, Computational Biology, Infectious Diseases
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figshare
Dataset . 2016
Provider: Datacite
Abstract
Abstract Background Wharton’s jelly-derived mesenchymal stem cells (WJ-MSCs) are gaining increasing interest as an alternative source of stem cells for regenerative medicine applications. Definitive endoderm (DE) specification is a prerequisite for the development of vital organs such as liver and pancreas. Hence, efficient induction of the DE lineage from stem cells is crucial for subsequent generation of clinically relevant cell types. Here we present a defined 3D differentiation protocol of WJ-MSCs into
Subjects
free text keywords: Biophysics, Biochemistry, Space Science, 29999 Physical Sciences not elsewhere classified, Cell Biology, Molecular Biology, Pharmacology, Biotechnology, 39999 Chemical Sciences not elsewhere classified, Developmental Biology, Cancer, Hematology, 110309 Infectious Diseases, Plant Biology, Computational Biology, Infectious Diseases
Download from
figshare
Dataset . 2016
Provider: Datacite
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