research data . Dataset . 2016

Spectrum of Cognitive Impairment in Korean ALS Patients without Known Genetic Mutations

Oh, Seong-il; Park, Aram; Kim, Hee-Jin; Oh, Ki-Wook; Choi, Hojin; Kwon, Min-Jung; Ki, Chang-Seok; Kim, Hee-Tae; Kim, Seung Hyun;
  • Published: 01 Jan 2016
  • Publisher: Figshare
Abstract
<div><p>Background</p><p>Cognitive impairment is associated with a negative prognosis in amyotrophic lateral sclerosis (ALS), as well as with clinical specificity. We investigate neuropsychological function in ALS patients without known genetic mutations in a Korean tertiary clinic.</p><p>Methods</p><p>Three hundred and eighteen patients were enrolled in a prospective longitudinal cohort from September 2008 to February 2012. At the time of diagnosis of sporadic ALS, we carried out genetic and comprehensive neuropsychological tests on all patients, and collected demographic and clinical characteristics. Six cognitive domains, namely executive function, attention,...
Subjects
free text keywords: Medicine, Biological Sciences, genetics, Human genetics, neuroscience, Cognitive neuroscience, cognition, neuropsychology, Mental health, psychology, neurology, Motor neuron diseases, amyotrophic lateral sclerosis, Cognitive neurology, dementia, impairment, korean, als, patients
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Dataset . 2016
Provider: figshare
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