research data . Dataset . 2016

A Novel Statistic for Genome-Wide Interaction Analysis

Wu, Xuesen; Dong, Hua; Luo, Li; Zhu, Yun; Peng, Gang; D. Reveille, John; Xiong, Momiao;
  • Published: 01 Jan 2016
  • Publisher: Figshare
Abstract
<div><p>Although great progress in genome-wide association studies (GWAS) has been made, the significant SNP associations identified by GWAS account for only a few percent of the genetic variance, leading many to question where and how we can find the missing heritability. There is increasing interest in genome-wide interaction analysis as a possible source of finding heritability unexplained by current GWAS. However, the existing statistics for testing interaction have low power for genome-wide interaction analysis. To meet challenges raised by genome-wide interactional analysis, we have developed a novel statistic for testing interaction between two loci (eith...
Subjects
free text keywords: Genetics, statistic, genome-wide, interaction
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Dataset . 2016
Provider: figshare
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