research data . Dataset . 2017

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Open Access
  • Published: 06 Apr 2017
Post-translational modifications of proteins (PTMs) act as key regulators of protein activity and of protein–protein interactions (PPIs). To date, it has been difficult to comprehensively explore functional links between PTMs and PPIs. To address this, we developed PTMOracle, a Cytoscape app for coanalyzing PTMs within PPI networks. PTMOracle also allows extensive data to be integrated and coanalyzed with PPI networks, allowing the role of domains, motifs, and disordered regions to be considered. For proteins of interest, or a whole proteome, PTMOracle can generate network visualizations to reveal complex PTM-associated relationships. This is assisted by OracleP...
free text keywords: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Cancer, Plant Biology, 69999 Biological Sciences not elsewhere classified, 80699 Information Systems not elsewhere classified, PTM-associated relationships, PTMOracle, protein, Coanalyzing Post-Translational Modifications, Cytoscape app store, Protein Interaction Networks Post-translational modifications, PPI networks
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Dataset . 2017
Provider: figshare
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