publication . Doctoral thesis . 2002

Avian IgY antibody : In vitro and in vivo

Carlander, David;
Open Access English
  • Published: 01 Jan 2002
  • Publisher: Uppsala universitet, Institutionen för medicinska vetenskaper
  • Country: Sweden
Abstract
Immunoglobulin Y (IgY) is the major antibody found in eggs from chicken (Gallus domesticus). IgY can be used as an alternative to mammalian antibodies normally used in research, and its use in immunotherapy has recently been proposed. Compared to mammalian antibodies, IgY possesses several biochemical advantages and its simple purification from egg yolk prevents a stressful moment in animal handling, as no bleeding is necessary. Small amount of antigen (1 mg) can be used to elicit an immune response in chickens and there are low intra-individual differences regarding antibody concentration found in yolk. By studying two chicken breeds and their cross, a genetic ...
Subjects
free text keywords: Medical sciences, Antigen production, chicken, cystic fibrosis, egg, ELISA, IgY, immunotherapy, Pseudomonas aeruginosa, yolk, MEDICIN OCH VÅRD, MEDICINE, MEDICIN
Related Organizations

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