publication . Article . 1986

How Good Is the Evidence?

Howard Bauchner;
  • Published: 15 Aug 1986 Journal: JAMA, volume 256, page 887 (issn: 0098-7484, Copyright policy)
  • Publisher: American Medical Association (AMA)
We assessed the extent to which studies of the association between breast-feeding and infection met four important methodological standards that relate to both the scientific validity and the generalizability of the studies. Of the 20 studies (14 cohort, six case-control), only six met three or four of the methodological standards. Four of these six studies found that breast-feeding was not protective against infections and two found that breast-feeding was protective against infections. In the three studies in which statistical adjustments were made for three additional potentially important confounding variables—size of the family, smoking of cigarettes by the...
free text keywords: General Medicine, Respiratory tract infections, Surgery, medicine.medical_specialty, medicine, Cohort, Generalizability theory, Breastfeeding, Confounding, Developed country, Cohort study, Scientific validity, business.industry, business
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