publication . Article . 1993

immediate angioplasty for acute myocardial infarction

Richard A. Lange; L. David Hillis;
  • Published: 11 Mar 1993 Journal: New England Journal of Medicine, volume 328, pages 726-728 (issn: 0028-4793, eissn: 1533-4406, Copyright policy)
  • Publisher: Massachusetts Medical Society
During the past 10 to 15 years, pathological and arteriographic studies have shown that Q-wave myocardial infarction is usually caused by an occlusive coronary arterial thrombus. Investigations have also shown that thrombolytic therapy can restore antegrade flow in the occluded artery, reduce the size of the infarct, and improve survival. Initially, thrombolytic agents were infused directly into the occluded coronary artery during cardiac catheterization, but later studies showed that intravenous administration offered similar efficacy without the delay, the need for angiographic equipment and skilled personnel, or the morbidity and mortality associated with eme...
free text keywords: Thrombus, medicine.disease, medicine, Cardiology, medicine.medical_specialty, Cardiac catheterization, medicine.medical_treatment, Surgery, Diabetes mellitus, Angioplasty, Internal medicine, Artery, medicine.anatomical_structure, business.industry, business, Thrombolytic Agent, Heart disease, Myocardial infarction
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