publication . Article . 1989

Recent developments in trace element metabolism and function: newer roles of selenium in nutrition.

Raymond F. Burk;
  • Published: 01 Jul 1989 Journal: The Journal of Nutrition, volume 119, pages 1,051-1,054 (issn: 0022-3166, eissn: 1541-6100, Copyright policy)
  • Publisher: Oxford University Press (OUP)
: Until recently, studies of the function of selenium focused on the selenoenzyme, glutathione peroxidase. However, the recognition that several metabolic effects of selenium are not associated with glutathione peroxidase has forced a re-evaluation of the function of this enzyme and the element. Hepatic glutathione peroxidase contains a significant percentage of the regulated selenium in the rat and is more sensitive to selenium deficiency than other selenoproteins. Thus, in addition to its enzymatic activity, it might have a storage function for the element. Another selenoprotein, designated selenoprotein P, has been found in rat plasma and has been quantitated...
Medical Subject Headings: integumentary systemfood and beveragesinorganic chemicals
free text keywords: Nutrition and Dietetics, Medicine (miscellaneous)
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