publication . Article . 2004

safety and efficacy of a proteolytic enzyme for enzymatic burn debridement a preliminary report

Lior Rosenberg; Oren Lapid; Alex Bogdanov-Berezovsky; Ronen Glesinger; Yuval Krieger; Eldad Silberstein; Amiram Sagi; Keith Judkins; Adam J. Singer;
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  • Published: 06 Nov 2004 Journal: Burns, volume 30, pages 843-850 (issn: 0305-4179, Copyright policy)
  • Publisher: Elsevier BV
Abstract
A prospective, non-comparative study design was used to describe our experience with a bromelain-derived debriding agent, Debridase, in 130 patients with 332 deep second degree and third degree burns treated between 1984 and 1999. Debridase was applied after saturating the burns with a moist dressing for 2‐24 h. Debridase was applied for a period of 4 h under an occlusive dressing. Mean patient age was 18.6 19.3, 42 (32.3%) were female, and 63 (48.5%) were children under age 18. Most burns were small. Debridase was applied once in 241 (72.6%)
Subjects
free text keywords: Medicine, business.industry, business, Third-Degree Burn, Occlusive dressing, Surgery, medicine.medical_specialty, Burn debridement
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