publication . Article . 2005

cardiac stem and progenitor cell biology for regenerative medicine

Daniele Torella; Georgina M. Ellison; Bernardo Nadal-Ginard; Ciro Indolfi;
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  • Published: 22 Sep 2005 Journal: Trends in Cardiovascular Medicine, volume 15, pages 229-236 (issn: 1050-1738, Copyright policy)
  • Publisher: Elsevier BV
Abstract
Stem cell therapy is a new and promising treatment of heart disease. However, the race is still on to find the “best” cell to reconstitute the myocardium and improve function after myocardial damage. The recent discovery in the adult mammalian myocardium of a small cell population with the phenotype, behavior, and regenerative potential of cardiac stem and progenitor cells has proposed these cells as the most appropriate for cell therapy. The existence of these cells has provided an explanation for the hitherto unexplained existence of a subpopulation of immature cycling myocytes in the adult myocardium. These findings have placed the heart squarely among other ...
Subjects
free text keywords: Cardiology and Cardiovascular Medicine, Cellular differentiation, Cardiology, medicine.medical_specialty, medicine, Immunology, Progenitor cell, Cell therapy, Regenerative medicine, Population, education.field_of_study, education, Cell biology, Stem-cell therapy, medicine.medical_treatment, Clinical uses of mesenchymal stem cells, Biology, Endothelial stem cell, Internal medicine
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