publication . Article . 2015

In situ synthesis of conductive polypyrrole on electrospun cellulose nanofibers: scaffold for neural tissue engineering

Johannes Thunberg; Theodoros Kalogeropoulos; Volodymyr Kuzmenko; Daniel Hägg; Gunnar Westman; Paul Gatenholm; Sara Johannesson;
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  • Published: 15 Mar 2015 Journal: Cellulose, volume 22, pages 1,459-1,467 (issn: 0969-0239, eissn: 1572-882X, Copyright policy)
  • Publisher: Springer Science and Business Media LLC
Abstract
This study reports the synthesis of conductive polypyrrole (PPy) on electrospun cellulose nanofibers. The cellulose nanofibers were electrospun via cellulose acetate and surface modified using in situ pyrrole polymerization. PPy adhered to the cellulose nanofiber surface as small particles and caused a 105 fold increase in conductivity compared to unmodified cellulose nanofibers. In addition, tests revealed no cytotoxic potential for the PPy coated cellulose nanofiber materials. In vitro culturing using SH-SY5Y human neuroblastoma cells indicated enhanced cell adhesion on the PPy coated cellulose material. SH-SY5Y cell viability was evident up to 15 days of diff...
Subjects
free text keywords: Polymers and Plastics, Fiber, Polypyrrole, chemistry.chemical_compound, chemistry, Chemical engineering, Tissue engineering, Cellulose acetate, Electrospinning, Nanofiber, Neural tissue engineering, Materials science, Cellulose, Polymer chemistry
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