publication . Article . 2011

Clinical Phenomenology and Neuroimaging Correlates in ALS-FTD

Catherine Lomen-Hoerth;
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  • Published: 05 Oct 2011 Journal: Journal of Molecular Neuroscience, volume 45, pages 656-662 (issn: 0895-8696, eissn: 1559-1166, Copyright policy)
  • Publisher: Springer Science and Business Media LLC
Abstract
The overlap of frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS) has been well documented in FTD patients with co-morbid motor neuron degeneration and in ALS patients with frontotemporal dysfunction. Up to 15% of FTD patients and 30% of ALS patients experience the overlap syndrome. The syndrome may be difficult to identify since patients often present either to a neuromuscular clinic or a memory disorder’s center, each which may have limited expertise in the other specialty. Survival is greatly impacted for both disorders in the co-morbid condition, making identification of this syndrome critical. The clinical characteristics of the overlap s...
Subjects
Medical Subject Headings: mental disorders
free text keywords: Amyotrophic lateral sclerosis, medicine.disease, medicine, Neuroimaging, Psychology, Overlap syndrome, Neurochemistry, Molecular biology, Clinical neurophysiology, medicine.medical_specialty, Frontotemporal dementia, Neurology, Neuroscience, Pediatrics, Memory disorder
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