publication . Article . 2012

Fatty acid composition of mid-trimester amniotic fluid in women of different ethnicities

Marilza Vieira Cunha Rudge;
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  • Published: 18 May 2012 Journal: The Journal of Maternal-Fetal & Neonatal Medicine, volume 25, pages 818-821 (issn: 1476-7058, eissn: 1476-4954, Copyright policy)
  • Publisher: Informa UK Limited
Abstract
Objective: To determine whether the fatty acid composition of mid-trimester amniotic fluid differs by ethnicity and pregnancy outcome. Methods: Fatty acid composition was analyzed by gas chromatography in 198 women undergoing amniocentesis at 15–19 weeks gestation. Cytokine levels were determined by ELISA in a subgroup of 52 subjects. Results: The major fatty acids detected were palmitic acid (31.8%) and stearic acid (31.5%). The n-6 polyunsaturated fatty acids (PUFA), linoleic acid (LA, 18:2) and arachidonic acid (AA, 20:4), were 11.3%, while the n-3 PUFA fatty acids, α linolenic acid (ALA, 18:3) and docosahexaenoic acid (DHA, 22:6), were 3.8% of the total. Pal...
Subjects
free text keywords: Obstetrics and Gynaecology, Pediatrics, Perinatology, and Child Health
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