publication . Article . 2008

Taxanes in Combination with Cisplatin and Fluorouracil for Advanced Penile Cancer: Preliminary Results

Nicola Nicolai;
  • Published: 16 Jul 2008 Journal: European Urology, volume 55, pages 546-551 (issn: 0302-2838, Copyright policy)
  • Publisher: Elsevier BV
Abstract Background Chemotherapy is emerging in the management of advanced penile cancer. Objective To evaluate the therapeutic activity of taxanes (T) in combination with cisplatin-fluorouracil (PF) for salvage of primarily unresectable or relapsed nodal metastases from squamous cell carcinoma (SCC) of the penis. Design, setting, and participants Six consecutive patients were treated at Istituto Nazionale Tumori (INT), Milano, with neoadjuvant paclitaxel, cisplatin, and 5-fluorouracil (TPF) for unresectable (two cases) or recurrent nodal metastases (four cases) from SCC of the penis from 2004 to 2006. Informed consent was given by all patients. Intervention Fou...
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