publication . Article . 2011

The use of rapid onset opioids for breakthrough cancer pain: The challenge of its dosing

Sebastiano Mercadante;
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  • Published: 07 Jan 2011 Journal: Critical Reviews in Oncology/Hematology, volume 80, pages 460-465 (issn: 1040-8428, Copyright policy)
  • Publisher: Elsevier BV
Abstract
Breakthrough cancer pain (BTcP) has been defined as a transitory increase in pain intensity on a baseline pain of moderate intensity in patients on analgesic treatment regularly administered. This review provides updated information about the use of opioids for the treatment of BTcP, with special emphasis on the use of new rapid onset opioids (ROOs). Due to its slow onset to effect oral opioids cannot be considered an efficacious treatment for BTcP. Parenteral opioids may provide rapid onset of analgesia, but not always available particularly at home. Different technologies have been developed to provide fast pain relief with potent opioid drugs such fentanyl, d...
Subjects
free text keywords: Oncology, Geriatrics and Gerontology, Hematology, General Medicine
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