publication . Article . 2012

Rapid quality assessment of Radix Aconiti Preparata using direct analysis in real time mass spectrometry.

Hongbin Zhu; Chunyan Wang; Yao Qi; Fengrui Song; Zhiqiang Liu; Shuying Liu;
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  • Published: 24 Sep 2012 Journal: Analytica Chimica Acta, volume 752, pages 69-77 (issn: 0003-2670, Copyright policy)
  • Publisher: Elsevier BV
Abstract
This study presents a novel and rapid method to identify chemical markers for the quality control of Radix Aconiti Preparata, a world widely used traditional herbal medicine. In the method, the samples with a fast extraction procedure were analyzed using direct analysis in real time mass spectrometry (DART MS) combined with multivariate data analysis. At present, the quality assessment approach of Radix Aconiti Preparata was based on the two processing methods recorded in Chinese Pharmacopoeia for the purpose of reducing the toxicity of Radix Aconiti and ensuring its clinical therapeutic efficacy. In order to ensure the safety and effectivity in clinical use, th...
Subjects
free text keywords: Analytical Chemistry, Spectroscopy, Biochemistry, Environmental Chemistry
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