publication . Article . 2005

The association of hypertension and diabetes: prevalence, cardiovascular risk and protection by blood pressure reduction

Giuseppe Mancia;
  • Published: 27 Apr 2005 Journal: Acta Diabetologica, volume 42, pages s17-s25 (issn: 0940-5429, eissn: 1432-5233, Copyright policy)
  • Publisher: Springer Science and Business Media LLC
Diabetes and hypertension frequently coexist, and their combination provides additive increases in the risk of life-threatening cardiovascular events. Recent guidelines agree on the need for early, aggressive reduction of blood pressure, with a goal of <130/80 mmHg, in patients with diabetes. The mechanism that underpins the increased sensitivity of diabetic subjects to hypertension is not known, but may involve impaired autoregulation or attenuated nocturnal decrease of blood pressure. All classes of antihypertensive agents are effective in reducing blood pressure in diabetic subjects, and all show evidence of a concomitant reduction in cardiovascular risk. Alt...
free text keywords: Internal Medicine, Endocrinology, Diabetes and Metabolism, Endocrinology, General Medicine, Diabetes mellitus, medicine.disease, medicine, Metabolic syndrome, Blood pressure, Type 2 diabetes, Combination therapy, Prehypertension, medicine.medical_specialty, business.industry, business, Cardiology, Risk factor, Concomitant
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