publication . Article . 2013

Endogenous opioids and nonsuicidal self-injury: A mechanism of affect regulation

Konrad Bresin; Kathryn H. Gordon;
  • Published: 20 Jan 2013 Journal: Neuroscience & Biobehavioral Reviews, volume 37, pages 374-383 (issn: 0149-7634, Copyright policy)
  • Publisher: Elsevier BV
Abstract Nonsuicidal self-injury (NSSI), or the purposeful destruction of body tissue occurring without suicidal intent, is a perplexing behavior as it goes against the natural instinct to maximize pleasure and minimize pain. One possible reason that people engage in NSSI is to regulate affect. However, the exact mechanisms that cause NSSI to lead to reduced feelings of negative affect remain unclear. Due to its involvement in the regulation of pain and emotion, the endogenous opioid system has been proposed to mediate the affect regulation effects of NSSI. The authors review evidence from multiple literatures to support this claim. Based on the current research...
free text keywords: Cognitive Neuroscience, Behavioral Neuroscience, Neuropsychology and Physiological Psychology
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