publication . Article . 1994

Extrapyramidal Signs and Psychiatric Symptoms Predict Faster Cognitive Decline in Alzheimer's Disease

Eugene Sobel; Helena Chang Chui; Scott A. Lyness; Lon S. Schneider;
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  • Published: 01 Jul 1994 Journal: Archives of Neurology, volume 51, pages 676-681 (issn: 0003-9942, Copyright policy)
  • Publisher: American Medical Association (AMA)
Abstract
Objective: To identify clinical predictors of cognitive decline in Alzheimer's disease. Design: A cohort of patients was followed up longitudinally and the likelihood of arriving at two cognitive end points was assessed using the Cox proportional hazards model and eight explanatory variables. Setting: Subjects were chosen from patients examined for memory loss at two medical centers affiliated with the University of Southern California, Los Angeles. Patients: The sample included 135 patients who met National Institute for Neurological and Communicative Disorders and Stroke—Alzheimer's Disease and Related Disorders Association criteria for probable or definite Al...
Subjects
free text keywords: Arts and Humanities (miscellaneous), Clinical Neurology, Psychomotor agitation, medicine.symptom, medicine, Cognitive disorder, medicine.disease, Confidence interval, Cognitive decline, Psychiatry, medicine.medical_specialty, Alzheimer's disease, Proportional hazards model, Cohort, Dementia, Psychology
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