publication . Article . 2011

Primary prophylactic human papillomavirus vaccination programs: future perspective on global impact

Julia ML Brotherton; Dorota M Gertig;
  • Published: 08 Aug 2011 Journal: Expert Review of Anti-infective Therapy, volume 9, pages 627-639 (issn: 1478-7210, eissn: 1744-8336, Copyright policy)
  • Publisher: Informa UK Limited
Of the 40 types of human papillomavirus that can infect the mucosal epithelium, four types can now be prevented using prophylactic vaccination. Two of these types (high-risk types 16 and 18) cause 70% of cervical cancers, a proportion of other genital cancers and a subset of head and neck cancers. The low-risk types 6 and 11 cause 90% of genital warts and the disease recurrent respiratory papillomatosis. Thus, if primary HPV vaccination programs can be implemented effectively, the potential for a reduction in global disease burden is great. This article considers the current issues and challenges in delivering primary HPV vaccination programs effectively and the...
free text keywords: Microbiology (medical), Microbiology, Virology, Infectious Diseases
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